Possible Underlying Mechanisms for the Renoprotective Effect of Retinoic Acid-Pretreated Wharton’s Jelly Mesenchymal Stem Cells against Renal Ischemia/Reperfusion Injury

Possible Underlying Mechanisms for the Renoprotective Effect of Retinoic Acid-Pretreated Wharton’s Jelly Mesenchymal Stem Cells against Renal Ischemia/Reperfusion Injury

Objectives: The current work investigated the effect of Wharton jelly mesenchymal stem cells (WJ-MSCs) pretreated with all-trans-retinoic acid (ATRA) on renal ischemia in rats and the possible role of oxidative stress, apoptotic and Wnt/β-Catenin signaling pathways, and inflammatory cytokines in the...

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Bibliographic Details
Main Authors: Mai Barakat, Abdelaziz M. Hussein, Mohamed F. Salama, Amira Awadalla, Nashwa Barakat, Mohamed Serria, Mohamed El-Shafey, Mohamed El-Sherbiny, Mohamed A. El Adl
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
retinoic acid
WJ-MSCs
Wnt/β-catenin
renal ischemia
Online Access:https://www.mdpi.com/2073-4409/11/13/1997

Internet

https://www.mdpi.com/2073-4409/11/13/1997

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