LexR Positively Regulates the LexABC Efflux Pump Involved in Self-Resistance to the Antimicrobial Di-N-Oxide Phenazine in Lysobacter antibioticus

LexR Positively Regulates the LexABC Efflux Pump Involved in Self-Resistance to the Antimicrobial Di-N-Oxide Phenazine in Lysobacter antibioticus

ABSTRACT Myxin, a di-N-oxide phenazine isolated from the soil bacterium Lysobacter antibioticus, exhibits potent activity against various microorganisms and has the potential to be developed as an agrochemical. Antibiotic-producing microorganisms have developed self-resistance mechanisms to protect...

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Bibliographic Details
Main Authors: Yangyang Zhao, Gaoge Xu, Zhizhou Xu, Baodian Guo, Fengquan Liu
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
myxin
phenazine
Lysobacter antibioticus
self-resistance
efflux pump
LysR family regulator
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04872-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04872-22

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