Inhibition of photoreceptor apoptosis in mice with retinitis pigmentosa through NF-κB/NLRP3 pathway suppression with Lycium barbarum polysaccharide

Inhibition of photoreceptor apoptosis in mice with retinitis pigmentosa through NF-κB/NLRP3 pathway suppression with Lycium barbarum polysaccharide

Objective: To explore whether Lycium barbarum polysaccharide (LBP) can reduce the apoptosis of retinal photoreceptor cells in retinitis pigmentosa (RP) mice by inhibiting nuclear factor-kappa B (NF-κB)/NOD-like receptor thermal protein domain-associated protein 3 (NLRP3) signaling pathway. Methods:...

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Bibliographic Details
Main Authors: Ying Wang, Ying Deng, Jing Lu, Jun Peng, Yasha Zhou, Yijing Yang, Qinghua Peng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Digital Chinese Medicine
Subjects:
Retinitis pigmentosa (RP)
Lycium barbarumpolysaccharide (LBP)
Apoptosis
NF-κB/NLRP3 pathway
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2589377723000563

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http://www.sciencedirect.com/science/article/pii/S2589377723000563

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