Is ongoing testosterone required after pubertal induction in Duchenne muscular dystrophy?

Is ongoing testosterone required after pubertal induction in Duchenne muscular dystrophy?

Glucocorticoids (GCs) reduce inflammation and preserve muscle function in boys with Duchenne muscular dystrophy (DMD) but cause pubertal delay. Pubertal induction with testosterone is recommended but longer-term outcome is unknown. Objective: To assess hypothalamic–pituitary–gonadal axis, muscle v...

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Bibliographic Details
Main Authors: Claire L Wood, Kieren G Hollingsworth, Edrina Bokaie, Eric Hughes, Robert Muni-Lofra, Anna Mayhew, Rod T Mitchell, Michela Guglieri, Joseph McElvaney, Timothy D Cheetham, Volker Straub
Format: Article
Language:English
Published: Bioscientifica 2023-10-01
Series:Endocrine Connections
Subjects:
puberty
duchenne muscular dystrophy
testosterone
muscle mri
Online Access:https://ec.bioscientifica.com/view/journals/ec/12/12/EC-23-0245.xml

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https://ec.bioscientifica.com/view/journals/ec/12/12/EC-23-0245.xml

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