Minocycline Improves Memory by Enhancing Hippocampal Synaptic Plasticity and Restoring Antioxidant Enzyme Activity in a Rat Model of Cerebral Ischemia-Reperfusion

Minocycline Improves Memory by Enhancing Hippocampal Synaptic Plasticity and Restoring Antioxidant Enzyme Activity in a Rat Model of Cerebral Ischemia-Reperfusion

Introduction: Oxidative stress plays a crucial role in the impairment of synaptic plasticity following cerebral ischemia, ultimately resulting in memory dysfunction. Hence, the applying antioxidant agents could be beneficial in managing memory deficits after brain ischemia. Minocycline is a tetracyc...

Full description

Bibliographic Details
Main Authors: Siavash Parvardeh, Mohammad Abbas Sheikholeslami, Shiva Ghafghazi, Ramin Pouriran, Seyed Erfan Mortazavi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2022-03-01
Series:Basic and Clinical Neuroscience
Subjects:
brain ischemia
memory
minocycline
synaptic plasticity
antioxidant enzymes
Online Access:http://bcn.iums.ac.ir/article-1-1604-en.html

Internet

http://bcn.iums.ac.ir/article-1-1604-en.html

Similar Items