A Biophysical Approach to the Identification of Novel ApoE Chemical Probes

Alzheimer’s disease (AD) is the most common type of dementia and, after age, the greatest risk factor for developing AD is the allelic variation of apolipoprotein E (ApoE), with homozygote carriers of the ApoE4 allele having an up to 12-fold greater risk of developing AD than noncarriers....

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Bibliographic Details
Main Authors: Lucas Kraft, Louise C. Serpell, John R. Atack
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/2/48