Evidence for inefficient contraction and abnormal mitochondrial activity in sarcopenia using magnetic resonance spectroscopy

Evidence for inefficient contraction and abnormal mitochondrial activity in sarcopenia using magnetic resonance spectroscopy

Abstract Background Mitochondrial dysfunction has been implicated in sarcopenia. 31P magnetic resonance spectroscopy (MRS) enables non‐invasive measurement of adenosine triphosphate (ATP) synthesis rates to probe mitochondrial function. Here, we assessed muscle energetics in older sarcopenic and non...

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Bibliographic Details
Main Authors: Mary C. Stephenson, Jamie X.M. Ho, Eugenia Migliavacca, Maria Kalimeri, Neerja Karnani, Subhasis Banerji, John J. Totman, Jerome N. Feige, Reshma A. Merchant, Stacey K.H. Tay
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Sarcopenia
Mitochondrial function
Spectroscopy
Muscle
Mitochondrial complex activity
Online Access:https://doi.org/10.1002/jcsm.13220

Internet

https://doi.org/10.1002/jcsm.13220

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