The Transglutaminase-2 Interactome in the APP23 Mouse Model of Alzheimer’s Disease

The Transglutaminase-2 Interactome in the APP23 Mouse Model of Alzheimer’s Disease

Amyloid-beta (Aβ) deposition in the brain is closely linked with the development of Alzheimer’s disease (AD). Unfortunately, therapies specifically targeting Aβ deposition have failed to reach their primary clinical endpoints, emphasizing the need to broaden the search strategy for alternative targe...

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Bibliographic Details
Main Authors: Micha M. M. Wilhelmus, Elisa Tonoli, Clare Coveney, David J. Boocock, Cornelis A. M. Jongenelen, John J. P. Brevé, Elisabetta A. M. Verderio, Benjamin Drukarch
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
transglutaminase-2
Alzheimer’s disease
amyloid-beta
interactome
mouse model
Online Access:https://www.mdpi.com/2073-4409/11/3/389

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https://www.mdpi.com/2073-4409/11/3/389

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