Discovery of Novel c-Jun N-Terminal Kinase 1 Inhibitors from Natural Products: Integrating Artificial Intelligence with Structure-Based Virtual Screening and Biological Evaluation

Discovery of Novel c-Jun N-Terminal Kinase 1 Inhibitors from Natural Products: Integrating Artificial Intelligence with Structure-Based Virtual Screening and Biological Evaluation

c-Jun N-terminal kinase 1 (JNK1) is currently considered a critical therapeutic target for type-2 diabetes. In recent years, there has been a great interest in naturopathic molecules, and the discovery of active ingredients from natural products for specific targets has received increasing attention...

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Bibliographic Details
Main Authors: Ruoqi Yang, Guiping Zhao, Bin Yan
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
JNK1
natural products
virtual screening
artificial intelligence
computer-aided drug design
Online Access:https://www.mdpi.com/1420-3049/27/19/6249

Internet

https://www.mdpi.com/1420-3049/27/19/6249

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