Zebrafish toxicological screening could aid Leishmaniosis drug discovery

Zebrafish toxicological screening could aid Leishmaniosis drug discovery

Abstract Background Recently a screen from a library of 1.8 million compounds identified in vitro a potent activity of the 2-aminobenzimidazoles series against Leishmania infantum, the etiological agent responsible by over 20.000 deaths each year. Several analogs were synthesized and in vitro tested...

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Bibliographic Details
Main Authors: Hirla Costa Silva Fukushima, Ricardo Lacava Bailone, Tatiana Corrêa, Helena Janke, Luís Kluwe De Aguiar, Princia Grejo Setti, Ricardo Carneiro Borra
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Laboratory Animal Research
Subjects:
3Rs
Animal health
Human health
Immunity
Leishmaniose
Toxicology
Online Access:https://doi.org/10.1186/s42826-021-00104-1

Internet

https://doi.org/10.1186/s42826-021-00104-1

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