Gut Microbiota and Intestinal Epithelial Myd88 Signaling Are Crucial for Renal Injury in UUO Mice

Gut Microbiota and Intestinal Epithelial Myd88 Signaling Are Crucial for Renal Injury in UUO Mice

Increasing evidence shows the essential participation of gut microbiota in human health and diseases by shaping local and systemic immunity. Despite an accumulating body of studies showing that chronic kidney disease (CKD) is closely associated with disturbances in the composition of gut microbiota,...

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Bibliographic Details
Main Authors: Ingrid Kazue Mizuno Watanabe, Magaiver Andrade-Silva, Orestes Foresto-Neto, Raphael José Ferreira Felizardo, Marco Aurélio Costa Matheus, Reinaldo Correa Silva, Marcos Antônio Cenedeze, Tâmisa Seeko Bandeira Honda, Luiz Augusto Buoro Perandini, Rildo Aparecido Volpini, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
chronic kidney disease
gut microbiota
Myd88
inflammation
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.578623/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.578623/full

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