Defined nanoscale chemistry influences delivery of peptido-toxins for cancer therapy.

We present an in-silico-to-in-vitro approach to develop well-defined, self-assembled, rigid-cored polymeric (Polybee) nano-architecture for controlled delivery of a key component of bee venom, melittin. A competitive formulation with lipid-encapsulated (Lipobee) rigid cored micelle is also synthesiz...

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Bibliographic Details
Main Authors: Santosh K Misra, Mao Ye, Sumin Kim, Dipanjan Pan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4452514?pdf=render