Heavy ion radiation exposure triggered higher intestinal tumor frequency and greater β-catenin activation than γ radiation in APC(Min/+) mice.

Heavy ion radiation exposure triggered higher intestinal tumor frequency and greater β-catenin activation than γ radiation in APC(Min/+) mice.

Risk of colorectal cancer (CRC) after exposure to low linear energy transfer (low-LET) radiation such as γ-ray is highlighted by the studies in atom bomb survivors. On the contrary, CRC risk prediction after exposure to high-LET cosmic heavy ion radiation exposure is hindered due to scarcity of in v...

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Manylion Llyfryddiaeth
Prif Awduron:	Kamal Datta, Shubhankar Suman, Bhaskar V S Kallakury, Albert J Fornace
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Public Library of Science (PLoS) 2013-01-01
Cyfres:	PLoS ONE
Mynediad Ar-lein:	http://europepmc.org/articles/PMC3605451?pdf=render

Eitemau Tebyg

Exposure to heavy ion radiation induces persistent oxidative stress in mouse intestine.
gan: Kamal Datta, et al.
Cyhoeddwyd: (2012-01-01)

Heavy-ion radiation-induced colitis and colorectal carcinogenesis in Il10-/- mice display co-activation of β-catenin and NF-κB signaling.
gan: Shubhankar Suman, et al.
Cyhoeddwyd: (2022-01-01)

Long-term differential changes in mouse intestinal metabolomics after γ and heavy ion radiation exposure.
gan: Amrita K Cheema, et al.
Cyhoeddwyd: (2014-01-01)

Administration of ON 01210.Na after exposure to ionizing radiation protects bone marrow cells by attenuating DNA damage response
gan: Suman Shubhankar, et al.
Cyhoeddwyd: (2012-01-01)

High-LET-Radiation-Induced Persistent DNA Damage Response Signaling and Gastrointestinal Cancer Development
gan: Kamendra Kumar, et al.
Cyhoeddwyd: (2023-06-01)

Decreased RXRα is associated with increased β-catenin/TCF4 in 56-Fe-induced intestinal tumors
gan: Shubhankar eSuman, et al.
Cyhoeddwyd: (2015-10-01)

8-OxodG: A Potential Biomarker for Chronic Oxidative Stress Induced by High-LET Radiation
gan: Kamendra Kumar, et al.
Cyhoeddwyd: (2024-08-01)

Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland
gan: Datta Kamal, et al.
Cyhoeddwyd: (2012-12-01)

Newly discovered genomic mutation patterns in radiation-induced small intestinal tumors of ApcMin/+ mice.
gan: Daisuke Iizuka, et al.
Cyhoeddwyd: (2023-01-01)

Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.
gan: Elahi, E, et al.
Cyhoeddwyd: (2009)

Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom 1R ApcMin/+ mice
gan: Elahi, E, et al.
Cyhoeddwyd: (2009)

Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.
gan: Eiram Elahi, et al.
Cyhoeddwyd: (2009-01-01)

Platelet status in cancer cachexia progression in ApcMin/+ mice
gan: Patrice Cunningham, et al.
Cyhoeddwyd: (2023-08-01)

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation
gan: Schneikert, Jean, et al.
Cyhoeddwyd: (2013)

Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation.
gan: Jean Schneikert, et al.
Cyhoeddwyd: (2013-01-01)

Dietary supplementation with black raspberries prolongs survival in ApcMin/+ mice
gan: Athena Dong, et al.
Cyhoeddwyd: (2021-09-01)

β-Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC
gan: Ernst Fredericks, et al.
Cyhoeddwyd: (2018-01-01)

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
gan: Haines, J, et al.
Cyhoeddwyd: (2005)

Liver inflammation and metabolic signaling in ApcMin/+ mice: the role of cachexia progression.
gan: Aditi A Narsale, et al.
Cyhoeddwyd: (2015-01-01)

Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of ApcMin/+ mice
gan: Zhenyu Zhong, et al.
Cyhoeddwyd: (2017-04-01)

Malic Enzyme 1 (ME1) is pro-oncogenic in ApcMin/+ mice
gan: Lorenzo M. Fernandes, et al.
Cyhoeddwyd: (2018-09-01)

Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in <it>Apc</it><sup>Min/+ </sup>mice
gan: Brudvik Kristoffer W, et al.
Cyhoeddwyd: (2011-12-01)

The interactions of APC, E-cadherin and beta-catenin in tumour development and progression.
gan: Ilyas, M, et al.
Cyhoeddwyd: (1997)

Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.
gan: Hao, X, et al.
Cyhoeddwyd: (2002)

Loss of heterozygosity at APC and beta-catenin expression in sporadic colorectal carcinogenesis
gan: Hao, X, et al.
Cyhoeddwyd: (1998)

Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.
gan: Sieber, O, et al.
Cyhoeddwyd: (2004)

Inulin impacts tumorigenesis promotion by colibactin-producing Escherichia coli in ApcMin/+ mice
gan: Manon Oliero, et al.
Cyhoeddwyd: (2023-02-01)

Chemopreventive Effects of RXR-Selective Rexinoid Bexarotene on Intestinal Neoplasia of ApcMin/+ Mice
gan: Naveena B. Janakiram, et al.
Cyhoeddwyd: (2012-02-01)

Fas/CD95 deficiency in ApcMin/+ mice increases intestinal tumor burden.
gan: Hector Guillen-Ahlers, et al.
Cyhoeddwyd: (2010-02-01)

Characterization of the male ApcMin/+ mouse as a hypogonadism model related to cancer cachexia
gan: James P. White, et al.
Cyhoeddwyd: (2013-11-01)

Therapeutic utility of aspirin in the <it>Apc</it><sup><it>Min</it>/+</sup> murine model of colon carcinogenesis
gan: Zhang Xiao-Jing, et al.
Cyhoeddwyd: (2002-08-01)

Are passive smoking, air pollution and obesity a greater mortality risk than major radiation incidents?
gan: Smith Jim T
Cyhoeddwyd: (2007-04-01)

The soluble IGF2 receptor reduces small intestine adenoma number in the Apc(Min/+) mouse
gan: Howell, J, et al.
Cyhoeddwyd: (2000)

Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with ApcMin/+ Mutation
gan: Michele Barone, et al.
Cyhoeddwyd: (2015-01-01)

Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.
gan: Vid Leko, et al.
Cyhoeddwyd: (2013-01-01)

Reciprocal influence of B cells and tumor macro and microenvironments in the ApcMin/+ model of colorectal cancer
gan: Francesca Mion, et al.
Cyhoeddwyd: (2017-08-01)

The Effect of Estradiol Administration on Muscle Mass Loss and Cachexia Progression in Female ApcMin/+ Mice
gan: Brittany R. Counts, et al.
Cyhoeddwyd: (2019-11-01)

Plant sterols induce intestinal tumor formation in gender-related manner in ApcMin mice
gan: Marttinen Maija, et al.
Cyhoeddwyd: (2012-06-01)

The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse.
gan: James P White, et al.
Cyhoeddwyd: (2011-01-01)

Editorial: Multifaceted Approaches Combining Low or High LET Radiation and Pharmacological Interventions in Cancer and Radioprotection: From Bench to Bedside
gan: Pankaj Chaudhary, et al.
Cyhoeddwyd: (2022-03-01)