Validation of the Antioxidant and Enzyme Inhibitory Potential of Selected Triterpenes Using In Vitro and In Silico Studies, and the Evaluation of Their ADMET Properties

Validation of the Antioxidant and Enzyme Inhibitory Potential of Selected Triterpenes Using In Vitro and In Silico Studies, and the Evaluation of Their ADMET Properties

The antioxidant and enzyme inhibitory potential of fifteen cycloartane-type triterpenes’ potentials were investigated using different assays. In the phosphomolybdenum method, cycloalpioside D (<b>6</b>) (4.05 mmol TEs/g) showed the highest activity. In 1,1-diphenyl-2-picrylhydrazyl (DPPH...

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Bibliographic Details
Main Authors: Nilufar Z. Mamadalieva, Fadia S. Youssef, Hidayat Hussain, Gokhan Zengin, Adriano Mollica, Nawal M. Al Musayeib, Mohamed L. Ashour, Bernhard Westermann, Ludger A. Wessjohann
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
antioxidants
enzyme inhibition
in vitro assays
triterpenes
virtual screening
inflammation
Online Access:https://www.mdpi.com/1420-3049/26/21/6331

Internet

https://www.mdpi.com/1420-3049/26/21/6331

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