An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission

An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission

Abstract SARS-CoV-2 is primarily transmitted through droplets and airborne aerosols, and in order to prevent infection and reduce viral spread vaccines should elicit protective immunity in the airways. The neonatal Fc receptor (FcRn) transfers IgG across epithelial barriers and can enhance mucosal d...

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Bibliographic Details
Main Authors: Weizhong Li, Tao Wang, Arunraj M. Rajendrakumar, Gyanada Acharya, Zizhen Miao, Berin P. Varghese, Hailiang Yu, Bibek Dhakal, Tanya LeRoith, Athira Karunakaran, Wenbin Tuo, Xiaoping Zhu
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42796-0

Internet

https://doi.org/10.1038/s41467-023-42796-0

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