Is the cerebellum the optimal reference region for intensity normalization of perfusion MR studies in early Alzheimer's disease?

The cerebellum is the region most commonly used as a reference when normalizing the intensity of perfusion images acquired using magnetic resonance imaging (MRI) in Alzheimer's disease (AD) studies. In addition, the cerebellum provides unbiased estimations with nuclear medicine techniques. Howe...

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Bibliographic Details
Main Authors: María Lacalle-Aurioles, Yasser Alemán-Gómez, Juan Adán Guzmán-De-Villoria, Isabel Cruz-Orduña, Javier Olazarán, José María Mateos-Pérez, María Elena Martino, Manuel Desco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873914?pdf=render