Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers

Peptides play a major role in the transmission of information to and from the central nervous system. However, because of their structural complexity, the development of pharmacological peptide-based therapeutics has been challenged by the lack of understanding of endogenous peptide evolution. The t...

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Bibliographic Details
Main Authors: David A. Lovejoy, David W. Hogg, Thomas L. Dodsworth, Fernando R. Jurado, Casey C. Read, Andrea L. D'Aquila, Dalia Barsyte-Lovejoy
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00730/full