Analysis of candidate genes for cleft lip ± cleft palate using murine single-cell expression data

Analysis of candidate genes for cleft lip ± cleft palate using murine single-cell expression data

Introduction: Cleft lip ± cleft palate (CL/P) is one of the most common birth defects. Although research has identified multiple genetic risk loci for different types of CL/P (i.e., syndromic or non-syndromic forms), determining the respective causal genes and understanding the relevant functional n...

Full description

Bibliographic Details
Main Authors: Anna Siewert, Benedikt Reiz, Carina Krug, Julia Heggemann, Elisabeth Mangold, Henning Dickten, Kerstin U. Ludwig
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cleft lip with or without cleft palate
single-cell RNA sequencing (scRNA-seq)
IRF6
craniofacial development
expression pattern
single-cell transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1091666/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1091666/full

Similar Items