Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch

Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch

Skin vaccination using biodegradable microneedle patch (MNP) technology in vaccine delivery is a promising strategy showing significant advantages over conventional flu shots. In this study, we developed an MNP encapsulating a 4M2e-tFliC fusion protein and two types of whole inactivated influenza vi...

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Bibliographic Details
Main Authors: Wandi Zhu, Song Li, Chao Wang, Guoying Yu, Mark R. Prausnitz, Bao-Zhong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
microneedle patch
skin vaccination
influenza vaccine
H7N9 influenza virus
immune responses
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01705/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01705/full

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