Partial Decay of Thiamine Signal Transduction Pathway Alters Growth Properties of Candida glabrata.

The phosphorylated form of thiamine (Vitamin B1), thiamine pyrophosphate (TPP) is essential for the metabolism of amino acids and carbohydrates in all organisms. Plants and microorganisms, such as yeast, synthesize thiamine de novo whereas animals do not. The thiamine signal transduction (THI) pathw...

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Bibliographic Details
Main Authors: Christine L Iosue, Nicholas Attanasio, Noor F Shaik, Erin M Neal, Sarah G Leone, Brian J Cali, Michael T Peel, Amanda M Grannas, Dennis D Wykoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4807840?pdf=render