Mathematically universal and biologically consistent astrocytoma genotype encodes for transformation and predicts survival phenotype

DNA alterations have been observed in astrocytoma for decades. A copy-number genotype predictive of a survival phenotype was only discovered by using the generalized singular value decomposition (GSVD) formulated as a comparative spectral decomposition. Here, we use the GSVD to compare whole-genome...

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Bibliographic Details
Main Authors: Katherine A. Aiello, Sri Priya Ponnapalli, Orly Alter
Format: Article
Language:English
Published: AIP Publishing LLC 2018-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5037882