Human dental pulp stem cells (hDPSCs) promote the lipofibroblast transition in the early stage of a fibro-inflammatory process

Human dental pulp stem cells (hDPSCs) promote the lipofibroblast transition in the early stage of a fibro-inflammatory process

Introduction: In autoimmune diseases, particularly in systemic sclerosis and chronic periaortitis, a strict correlation between chronic inflammation and fibrosis exists. Since the currently used drugs prove mostly effective in suppressing inflammation, a better comprehension of the molecular mechani...

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Main Authors: Alessandra Pisciotta, Rosanna Di Tinco, Giulia Bertani, Giulia Orlandi, Laura Bertoni, Elisa Pignatti, Monia Orciani, Paola Sena, Jessika Bertacchini, Carlo Salvarani, Gianluca Carnevale
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human dental pulp stem cells
pericytes
immunomodulation
fibrosis
TGF-β1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1196023/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1196023/full

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