Synthesis of Steroidal Thiadiazoles from Steroidal Ketones

Synthesis of Steroidal Thiadiazoles from Steroidal Ketones

Syntheses of steroidal heterocycles containing a five-membered N,S- heterocycle attached at the 6,7 positions of the B ring are reported. 5α-Cholestane-6-one (1), its 3β-acetoxy- (2) and 3β-chloro- (3) analogues reacted with semicarbazide and aqueous sodium acetate in refluxing ethanol to y...

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Bibliographic Details
Main Authors: M. Akhtar, M. Alam, M. Mushfiq
Format: Article
Language:English
Published: MDPI AG 2005-08-01
Series:Molecules
Subjects:
Thiadiazoles
steroidal thiadiazoles
steroidal heterocycles
cyclization
thionyl chloride
semicarbazide
dichloromethane.
Online Access:http://www.mdpi.com/1420-3049/10/7/803/

Internet

http://www.mdpi.com/1420-3049/10/7/803/

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