A Genital Infection-Attenuated <named-content content-type="genus-species">Chlamydia muridarum</named-content> Mutant Infects the Gastrointestinal Tract and Protects against Genital Tract Challenge

A Genital Infection-Attenuated <named-content content-type="genus-species">Chlamydia muridarum</named-content> Mutant Infects the Gastrointestinal Tract and Protects against Genital Tract Challenge

ABSTRACT Chlamydia spp. productively infect mucosal epithelial cells of multiple anatomical sites, including the conjunctiva, lungs, gastrointestinal (GI) tract, and urogenital tract. We, and others, previously established that chlamydial GI tropism is mediated by distinct chromosomal and plasmid fa...

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Bibliographic Details
Main Authors: Sandra G. Morrison, Amanda M. Giebel, Evelyn Toh, Arkaprabha Banerjee, David E. Nelson, Richard P. Morrison
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
Chlamydia
animal models
genital tract immunity
intracellular pathogen
pathogenesis
virulence
Online Access:https://journals.asm.org/doi/10.1128/mBio.02770-20

Internet

https://journals.asm.org/doi/10.1128/mBio.02770-20

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