Inflammation-Related Immune-Modulatory SLURP1 Prevents the Proliferation of Human Colon Cancer Cells, and Its Delivery by <i>Salmonella</i> Demonstrates Cross-Species Efficacy against Murine Colon Cancer

Inflammation-Related Immune-Modulatory SLURP1 Prevents the Proliferation of Human Colon Cancer Cells, and Its Delivery by <i>Salmonella</i> Demonstrates Cross-Species Efficacy against Murine Colon Cancer

This study investigates the anticancer properties of the α7-nAChR antagonist SLURP1 with a specific focus on its effect as an inflammation modulator on human colorectal cancer cell lines Caco2, Colo320DM, and H508 cells. The investigation includes the evaluation of cell cycle arrest, cell migration...

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Bibliographic Details
Main Authors: Amal Senevirathne, Ram Prasad Aganja, Chamith Hewawaduge, John Hwa Lee
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceutics
Subjects:
α7-nAChR
SLURP1
colorectal cancer
receptor inhibitor
cell cycle
<i>Salmonella</i>
Online Access:https://www.mdpi.com/1999-4923/15/10/2462

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https://www.mdpi.com/1999-4923/15/10/2462

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