Antioxidant activity of isolated compounds from ethyl acetate extract of Bruguiera parviflora

Bruguiera parviflora belongs to Bruguiera genus, which possesses several biological activities such as antidiabetic, anti-inflammatory, and antioxidant. Phytochemical investigation of the ethyl acetate extract from Bruguiera parviflora leaves was carried out bioassay-guided isolation and obtained th...

Full description

Bibliographic Details
Main Authors: Bui Thanh Tung, Nguyen Thi Le Thuy
Format: Article
Language:English
Published: HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE 2022-11-01
Series:Ho Chi Minh City Open University Journal of Science - Engineering and Technology
Subjects:
Online Access:https://journalofscience.ou.edu.vn/index.php/tech-en/article/view/2329
Description
Summary:Bruguiera parviflora belongs to Bruguiera genus, which possesses several biological activities such as antidiabetic, anti-inflammatory, and antioxidant. Phytochemical investigation of the ethyl acetate extract from Bruguiera parviflora leaves was carried out bioassay-guided isolation and obtained three known compounds, namely kochioside A (1), oleanolic acid (2) and quercitrin (3). The chemical structures of isolated compounds were identified by spectroscopic method and comparison with previously published data. All isolated compounds were evaluated for antioxidant activity with the free radical scavenging ability on 1,1-diphenyl-2-picrylhydrazyl (DPPH). Among them, quercitrin (3) was the most potent compound against DPPH radical with the IC50 value of 16.4 ± 0.2 µg/mL, compared to vitamin C, which was used as a positive control.
ISSN:2734-9330
2734-9608