Conformational transitions and allosteric modulation in a heteromeric glycine receptor
Glycine receptors (GlyR) are a critical postsynaptic component of spinal neurons. Here, the auhtors present cryo-EM structures of a heteromeric GlyR in the presence of an antagonist, agonist and agonist with a positive allosteric modulator.
| Auteurs principaux: | , , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Nature Portfolio
2023-03-01
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| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-023-37106-7 |