Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae.

The mosquito Anopheles gambiae uses its innate immune system to control bacterial and Plasmodium infection of its midgut tissue. The activation of potent IMD pathway-mediated anti-Plasmodium falciparum defenses is dependent on the presence of the midgut microbiota, which activate this defense system...

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Bibliographic Details
Main Authors: Benjamin J Blumberg, Stefanie Trop, Suchismita Das, George Dimopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3760850?pdf=render