Novel therapeutics in myeloproliferative neoplasms

Novel therapeutics in myeloproliferative neoplasms

Abstract Hyperactive signaling of the Janus-Associated Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) pathway is central to the pathogenesis of Philadelphia-chromosome-negative myeloproliferative neoplasms (MPN), i.e., polycythemia vera (PV), essential thrombocythemia (ET), and...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Sangeetha Venugopal, John Mascarenhas
Format:	Artikel
Sprache:	English
Veröffentlicht:	BMC 2020-12-01
Schriftenreihe:	Journal of Hematology & Oncology
Schlagworte:	MF ET PV JAK-STAT CALR Ruxolitinib
Online Zugang:	https://doi.org/10.1186/s13045-020-00995-y

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