Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis

Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis

Viral myocarditis is pathologically associated with RNA viruses such as coxsackievirus B3 (CVB3), or more recently, with SARS-CoV-2, but despite intensive research, clinically proven treatment is limited. Here, by use of a transgenic mouse strain (TG) containing a CVB3ΔVP0 genome we unravel virus-me...

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Bibliographic Details
Main Authors: Matthias Rohrbeck, Verena Hoerr, Ilaria Piccini, Boris Greber, Jan Sebastian Schulte, Sara-Sophie Hübner, Elena Jeworutzki, Carsten Theiss, Veronika Matschke, Jörg Stypmann, Andreas Unger, Huyen Tran Ho, Paul Disse, Nathalie Strutz-Seebohm, Cornelius Faber, Frank Ulrich Müller, Stephan Ludwig, Ursula Rescher, Wolfgang A. Linke, Karin Klingel, Karin Busch, Stefan Peischard, Guiscard Seebohm
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
CVB3
myocarditis
contractility
cardiac dysfunction
calcium homeostasis
Online Access:https://www.mdpi.com/2073-4409/12/4/550

Internet

https://www.mdpi.com/2073-4409/12/4/550

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