Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies

Structure, Activation, and Regulation of NOX2: At the Crossroad between the Innate Immunity and Oxidative Stress-Mediated Pathologies

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) is a multisubunit enzyme complex that participates in the generation of superoxide or hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and plays a key role in several biological functions. Among seven known NOX i...

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Bibliographic Details
Main Authors: Cristina Nocella, Alessandra D’Amico, Vittoria Cammisotto, Simona Bartimoccia, Valentina Castellani, Lorenzo Loffredo, Leonardo Marini, Giulia Ferrara, Matteo Testa, Giulio Motta, Beatrice Benazzi, Fabio Zara, Giacomo Frati, Sebastiano Sciarretta, Pasquale Pignatelli, Francesco Violi, Roberto Carnevale, Smile Group
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
NOX2
oxidative stress
inflammation
immunity
therapeutics
Online Access:https://www.mdpi.com/2076-3921/12/2/429

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https://www.mdpi.com/2076-3921/12/2/429

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