The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity

Abstract In conjunction with previous studies, we have noted that ferroptosis, as an emerging mode of regulated cell death (RCD), is intimately related to anthracycline pharmacotherapy. Not only does ferroptosis significantly modulate tumour resistance and drug toxicity, which are core links of the...

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Bibliographic Details
Main Authors: Jiazheng Zhao, Ning Zhang, Xiaowei Ma, Ming Li, Helin Feng
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01483-1