Destabilization of the outer and inner mitochondrial membranes by core and linker histones.

<h4>Background</h4>Extensive DNA damage leads to apoptosis. Histones play a central role in DNA damage sensing and may mediate signals of genotoxic damage to cytosolic effectors including mitochondria.<h4>Methodology/principal findings</h4>We have investigated the effects of...

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Detalhes bibliográficos
Principais autores: Annunziata Cascone, Celine Bruelle, Dan Lindholm, Paolo Bernardi, Ove Eriksson
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2012-01-01
coleção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22523586/?tool=EBI