Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis

Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis

Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of intense research. Epstein-Barr virus (EBV), as a persistent and frequently reactivating virus with major immunogenic influences and a near...

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Bibliographic Details
Main Authors: Ute-Christiane Meier, Richard Christopher Cipian, Abbas Karimi, Ranjan Ramasamy, Jaap Michiel Middeldorp
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
Epstein-Barr virus
human endogenous retrovirus-W
inflammatory cascade
molecular mimicry
multiple sclerosis
human herpesvirus-6
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.757302/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.757302/full

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