A Microfluidic In Vitro Three-Dimensional Dynamic Model of the Blood–Brain Barrier to Study the Transmigration of Immune Cells

To study the biodistribution of new chemical and biological entities, an in vitro model of the blood–brain barrier (BBB) may become an essential tool during early phases of drug discovery. Here, we present a proof-of-concept of an in-house designed three-dimensional BBB biochip designed by us. This...

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Bibliographic Details
Main Authors: Megha Meena, Robin Vandormael, Maxime De Laere, Isabel Pintelon, Zwi Berneman, Regan Watts, Nathalie Cools
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/12/10/1293