The challenging nature of primary T lymphocytes for transfection: Effect of protamine sulfate on the transfection efficiency of chemical transfection reagents

Background and purpose: The optimization of an effective non-viral gene delivery method for genetic manipulation of primary human T cells has been a major challenge in immunotherapy researches. Due to the poor transfection efficiency of conventional methods in T cells, there has been an effort to in...

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Bibliographic Details
Main Authors: Ilnaz Rahimmanesh, Mehdi Totonchi, Hossein Khanahmad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2020;volume=15;issue=5;spage=437;epage=446;aulast=Rahimmanesh