Gut Microbial Perturbation and Host Response Induce Redox Pathway Upregulation along the Gut–Liver Axis during Giardiasis in C57BL/6J Mouse Model

Gut Microbial Perturbation and Host Response Induce Redox Pathway Upregulation along the Gut–Liver Axis during Giardiasis in C57BL/6J Mouse Model

Apicomplexan infections, such as giardiasis and cryptosporidiosis, negatively impact a considerable proportion of human and commercial livestock populations. Despite this, the molecular mechanisms of disease, particularly the effect on the body beyond the gastrointestinal tract, are still poorly und...

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Bibliographic Details
Main Authors: Avinash V. Karpe, Melanie L. Hutton, Steven J. Mileto, Meagan L. James, Chris Evans, Amol B. Ghodke, Rohan M. Shah, Suzanne S. Metcalfe, Jian-Wei Liu, Tom Walsh, Dena Lyras, Enzo A. Palombo, David J. Beale
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
host–parasite interactions
systems biology
giardiasis
gut–liver axis
integrated multiomics
metabolic pathways
Online Access:https://www.mdpi.com/1422-0067/24/2/1636

Internet

https://www.mdpi.com/1422-0067/24/2/1636

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