Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.

Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.

Iron chelators are used to treat iron overload cardiomyopathy patients. However, a direct comparison of the benefits of three common iron chelators (deferoxamine (DFO), deferiprone (DFP) and deferasirox (DFX)) or an antioxidant (N-acetyl cysteine (NAC)) with a combined DFP and NAC treatments on left...

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Bibliografski detalji
Glavni autori: Suwakon Wongjaikam, Sirinart Kumfu, Juthamas Khamseekaew, Jirapas Sripetchwandee, Somdet Srichairatanakool, Suthat Fucharoen, Siriporn C Chattipakorn, Nipon Chattipakorn
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC4948821?pdf=render

Internet

http://europepmc.org/articles/PMC4948821?pdf=render

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