Apicomplexan phosphodiesterases in cyclic nucleotide turnover: conservation, function, and therapeutic potential

Apicomplexan phosphodiesterases in cyclic nucleotide turnover: conservation, function, and therapeutic potential

ABSTRACT Apicomplexa encompasses a large number of intracellular parasites infecting a wide range of animals. Cyclic nucleotide signaling is crucial for a variety of apicomplexan life stages and cellular processes. The cyclases and kinases that synthesize and respond to cyclic nucleotides (i.e., 3′,...

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Bibliographic Details
Main Authors: William J. Moss, Lorenzo Brusini, Ronja Kuehnel, Mathieu Brochet, Kevin M. Brown
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mBio
Subjects:
phosphodiesterase
PDE
cyclic nucleotide
cGMP
cAMP
parasite
Online Access:https://journals.asm.org/doi/10.1128/mbio.03056-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03056-23

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