Transcriptomics and Proteomics Analyses Reveal JAK Signaling and Inflammatory Phenotypes during Cellular Senescence in Blind Mole Rats: The Reflections of Superior Biology

Transcriptomics and Proteomics Analyses Reveal JAK Signaling and Inflammatory Phenotypes during Cellular Senescence in Blind Mole Rats: The Reflections of Superior Biology

The blind mole rat (BMR), a long-living subterranean rodent, is an exceptional model for both aging and cancer research since they do not display age-related phenotypes or tumor formation. The Janus kinase–signal transducer and activator of transcription (JAK–STAT) signaling is a cytokine-stimulated...

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Bibliographic Details
Main Authors: Nurcan Inci, Erdogan Oguzhan Akyildiz, Abdullah Alper Bulbul, Eda Tahir Turanli, Emel Akgun, Ahmet Tarik Baykal, Faruk Colak, Perinur Bozaykut
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biology
Subjects:
aging
cancer
cellular senescence
JAK–STAT
SASP
inflammation
Online Access:https://www.mdpi.com/2079-7737/11/9/1253

Internet

https://www.mdpi.com/2079-7737/11/9/1253

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