TM2D3, a mammalian homologue of Drosophila neurogenic gene product Almondex, regulates surface presentation of Notch receptors

Abstract Notch signaling is an evolutionarily conserved mechanism required for numerous types of cell fate decisions in metazoans. It mediates short-range communication between cells with receptors and ligands, both of which are expressed on the cell surfaces. In response to the ligand-receptor inte...

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Bibliographic Details
Main Authors: Wataru Masuda, Tomoko Yamakawa, Rieko Ajima, Katsuya Miyake, Toshifumi Umemiya, Kazuhiko Azuma, Jun-ichi Tamaru, Makoto Kiso, Puspa Das, Yumiko Saga, Kenji Matsuno, Motoo Kitagawa
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-46866-7