Regulation of AmpC-Driven β-Lactam Resistance in Pseudomonas aeruginosa: Different Pathways, Different Signaling

Regulation of AmpC-Driven β-Lactam Resistance in Pseudomonas aeruginosa: Different Pathways, Different Signaling

ABSTRACT The hyperproduction of the chromosomal AmpC β-lactamase is the main mechanism driving β-lactam resistance in Pseudomonas aeruginosa, one of the leading opportunistic pathogens causing nosocomial acute and chronic infections in patients with underlying respiratory diseases. In the current sc...

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Bibliographic Details
Main Authors: Gabriel Torrens, Sara Belén Hernández, Juan Alfonso Ayala, Bartolome Moya, Carlos Juan, Felipe Cava, Antonio Oliver
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSystems
Subjects:
AmpC β-lactamase
Pseudomonas aeruginosa
muropeptide
peptidoglycan
Online Access:https://journals.asm.org/doi/10.1128/msystems.00524-19

Internet

https://journals.asm.org/doi/10.1128/msystems.00524-19

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