Testosterone induces sexual dimorphism during infection with Plasmodium berghei ANKA

Malaria is the most lethal parasitic disease worldwide; men exhibit higher mortality and more severe symptomatology than women; however, in most studies of immune response in malaria, sex is not considered a variable. Sex hormones 17β-oestradiol and testosterone are responsible for the main physiolo...

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Main Authors: Jesús Aguilar-Castro, Luis Antonio Cervantes-Candelas, Fidel Orlando Buendía-González, Omar Fernández-Rivera, Teresita de Jesús Nolasco-Pérez, Monserrat Sofía López-Padilla, David Roberto Chavira-Ramírez, Armando Cervantes-Sandoval, Martha Legorreta-Herrera
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.968325/full