Long-Term Blockade of Nociceptive Na<sub>v</sub>1.7 Channels Is Analgesic in Rat Models of Knee Arthritis
The voltage gated sodium channels (Na<sub>v</sub>) 1.7, 1.8, and 1.9 are primarily located on nociceptors where they are involved in signalling neuropathic pain. This study examined the effect of Na<sub>v</sub>1.7 blockade on joint pain using either the small molecule inhibit...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/12/11/1571 |