The benefits of clustering in TNF receptor superfamily signaling
The tumor necrosis factor (TNF) receptor superfamily is a structurally and functionally related group of cell surface receptors that play crucial roles in various cellular processes, including apoptosis, cell survival, and immune regulation. This review paper synthesizes key findings from recent stu...
| Những tác giả chính: | , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Frontiers Media S.A.
2023-08-01
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| Loạt: | Frontiers in Immunology |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1225704/full |
| Tóm tắt: | The tumor necrosis factor (TNF) receptor superfamily is a structurally and functionally related group of cell surface receptors that play crucial roles in various cellular processes, including apoptosis, cell survival, and immune regulation. This review paper synthesizes key findings from recent studies, highlighting the importance of clustering in TNF receptor superfamily signaling. We discuss the underlying molecular mechanisms of signaling, the functional consequences of receptor clustering, and potential therapeutic implications of targeting surface structures of receptor complexes. |
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| số ISSN: | 1664-3224 |