New Bioactive Azaartemisinin Derivatives

Reaction of artemisinin (1) with ethanolamine, followed by acid treatment produced the lactam (4S,8S,9S,13S,1R,5R,12R)-11-aza-11-(2-hydroxyethyl)-1,5,9-trimethyl-14,15-dioxatetracyclo [10.2.1.0<4,13>.0<8,13>]pentadecan-10-one (4) and the diol (1S,2S,6S,7S,5R,8R)-4-aza-5,6-dihydroxy-4-(2-...

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Bibliographic Details
Main Authors: Farouk S. El-Feraly, Ahlam M. Al-Fishawi, Mohamed S. Ahmad, Ahmed M. Galal, Mai M. Al-Oqail
Format: Article
Language:English
Published: MDPI AG 2003-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/8/12/901/