SuPAR mediates viral response proteinuria by rapidly changing podocyte function

SuPAR mediates viral response proteinuria by rapidly changing podocyte function

Abstract Elevation in soluble urokinase receptor (suPAR) and proteinuria are common signs in patients with moderate to severe coronavirus disease 2019 (COVID-19). Here we characterize a new type of proteinuria originating as part of a viral response. Inoculation of severe acute respiratory syndrome...

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Bibliographic Details
Main Authors: Changli Wei, Prasun K. Datta, Florian Siegerist, Jing Li, Sudhini Yashwanth, Kwi Hye Koh, Nicholas W. Kriho, Anis Ismail, Shengyuan Luo, Tracy Fischer, Kyle T. Amber, David Cimbaluk, Alan Landay, Nicole Endlich, Jay Rappaport, Michigan Medicine COVID−19 Investigators, Salim S. Hayek, Jochen Reiser
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40165-5

Internet

https://doi.org/10.1038/s41467-023-40165-5

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