Evaluation of the Ability of PAMPA Membranes to Emulate Biological Processes through the Abraham Solvation Parameter Model

Evaluation of the Ability of PAMPA Membranes to Emulate Biological Processes through the Abraham Solvation Parameter Model

Two parallel artificial membrane permeability assay (PAMPA) systems intended for emulating skin permeability have been characterized through the solvation parameter model of Abraham using multilinear regression analysis. The coefficients of the obtained equations have been compared to the ones alrea...

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Bibliographic Details
Main Authors: Sara Soriano-Meseguer, Elisabet Fuguet, Adriana Port, Martí Rosés
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Membranes
Subjects:
skin permeation
human intestinal absorption
blood-brain permeation
blood-brain partition
PAMPA
solvation parameter model
Online Access:https://www.mdpi.com/2077-0375/13/7/640

Internet

https://www.mdpi.com/2077-0375/13/7/640

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