Intervertebral disc cell fate during aging and degeneration: apoptosis, senescence, and autophagy

Intervertebral disc cell fate during aging and degeneration: apoptosis, senescence, and autophagy

ABSTRACT: Background: Degenerative disc disease, a major cause of low back pain and associated neurological symptoms, is a global health problem with the high morbidity, workforce loss, and socioeconomic burden. The present surgical strategy of disc resection and/or spinal fusion results in the fun...

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Bibliographic Details
Main Authors: Takashi Yurube, M.D., Ph.D., Yoshiki Takeoka, M.D., Ph.D., Yutaro Kanda, M.D., Ph.D., Ryosuke Kuroda, M.D., Ph.D., Kenichiro Kakutani, M.D., Ph.D.
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:North American Spine Society Journal
Subjects:
Intervertebral disc
Aging
Degeneration
Phenotype
Apoptosis
Senescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2666548423000124

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http://www.sciencedirect.com/science/article/pii/S2666548423000124

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