Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya.

Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV-exposed, seronegative female sex workers in Kenya.

Identifying the immune correlates of reduced susceptibility to HIV remains a key goal for the HIV vaccine field, and individuals who are HIV-exposed, seronegative (HESN) may offer important clues. Reduced systemic immune activation has been described in HESN individuals. Conversely, pro-inflammatory...

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Bibliographic Details
Main Authors: Duncan Chege, Yijie Chai, Sanja Huibner, Taylor Kain, Charles Wachihi, Makubo Kimani, Samson Barasa, Lyle R McKinnon, Festus K Muriuki, Anthony Kariri, Walter Jaoko, Omu Anzala, Joshua Kimani, T Blake Ball, Francis A Plummer, Rupert Kaul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425491?pdf=render

Internet

http://europepmc.org/articles/PMC3425491?pdf=render

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